Recent research from Mount Sinai has unveiled troubling findings regarding the exposure of fetuses to PFAS, commonly referred to as “forever chemicals.” The study, which analysed umbilical cord blood samples, revealed that fetuses are likely exposed to a far greater variety and concentration of these harmful compounds than previously understood. This significant discovery raises urgent questions about the potential health implications for newborns.
Uncovering the Scope of PFAS Exposure
Traditionally, testing of umbilical cord blood has focused on a limited range of PFAS compounds, primarily PFOA and PFOS. However, the expansive nature of PFAS—encompassing approximately 15,000 different chemicals—necessitates a more thorough examination. The new study examined 120 samples and employed a “non-targeted analysis” method, allowing researchers to identify 42 distinct PFAS compounds within the tested blood. The total concentration of these chemicals was also found to be substantially higher than prior estimates.
Co-author Shelley Liu, an associate professor at the Icahn School of Medicine, emphasised the importance of these findings, stating, “Babies are exposed to many more PFAS than we previously thought.” The vulnerability of fetuses during this critical developmental period highlights the pressing need for increased awareness and understanding of these exposures.
The Health Risks of PFAS
PFAS are used extensively for their water-, stain-, and grease-resistant properties in a multitude of consumer products. However, these chemicals have been linked to a range of serious health issues, including cancer, birth defects, weakened immunity, and various chronic diseases. Their moniker, “forever chemicals,” derives from their persistent nature, as they do not naturally decompose in the environment.

A comprehensive review of 40 studies has indicated that PFAS have been detected in 30,000 umbilical cord blood samples, suggesting that these chemicals are prevalent in the fetal environment. Elevated PFAS levels in mothers have been correlated with increased infant mortality rates, as well as issues such as low birth weight and long-term obesity. Moreover, exposure during pregnancy has been associated with long-term health conditions, including cancer and cardiovascular disease.
Regulatory Oversight and Analysis Limitations
The study underscores a significant gap in regulatory practices. Current testing methods employed by the U.S. Environmental Protection Agency (EPA) typically focus on a limited number of PFAS compounds, around 30 to 40, despite the existence of thousands of variants. A 2022 analysis revealed that regulatory bodies often underestimate PFAS levels in water due to outdated testing approaches.
The Mount Sinai study employed a more thorough analytical method that detected 31 PFAS compounds absent from the EPA’s certified blood test. While the newly certified blood test identifies 53 compounds, Liu pointed out that the expanded testing is still insufficient compared to the comprehensive analysis performed by her team.
Implications for Future Research and Policy
Although the Mount Sinai study did not directly assess specific health outcomes, the correlation between higher PFAS levels and increased health risks is well-documented. Liu and her colleagues plan to further investigate the health implications of their findings, aiming to contribute to a clearer understanding of how these chemicals affect development and health in infants.

David Andrews, acting chief science officer at the Environmental Working Group, highlighted the need for stringent regulatory measures, stating, “This paper is a stark reminder of the importance of health-protective regulations and how lax oversight can result in babies being born pre-polluted with harmful chemicals such as PFAS.”
Why it Matters
The revelations from this study present a clarion call for immediate action. As we grapple with the implications of these findings, it becomes increasingly clear that our regulatory frameworks must evolve to adequately safeguard the health of our most vulnerable populations—our children. With rising evidence linking PFAS exposure to dire health risks, it is imperative that policymakers prioritise robust regulations and invest in research that addresses the full scope of these chemicals in our environment. Only then can we hope to protect future generations from the insidious effects of pollution and ensure a healthier planet for all.