The Perils of Mixing Coffee and Common Medications

Michael Okonkwo, Middle East Correspondent
3 Min Read
⏱️ 2 min read

As many of us start our day with a comforting cup of coffee, it’s important to be aware that this seemingly harmless beverage can actually interfere with the effectiveness of certain medications. From cold and flu remedies to antidepressants and heart medications, caffeine’s impact on the body goes far beyond a quick energy boost.

According to Dipa Kamdar, a Senior Lecturer in Pharmacy Practice at Kingston University, the interactions between coffee and various drugs can lead to a range of issues, including amplified side effects, reduced absorption, and even altered drug metabolism. For instance, the combination of caffeine and decongestants like pseudoephedrine can cause jitters, headaches, and a rapid heart rate. Similarly, drinking coffee too soon after taking levothyroxine for an underactive thyroid can reduce the drug’s absorption by up to 50%.

The same timing rule applies to a class of osteoporosis medications called bisphosphonates, which also require an empty stomach and around 30-60 minutes before food or drink is consumed. Antidepressants and antipsychotics can also be affected, as caffeine can bind to these drugs in the stomach, potentially reducing their effectiveness.

Painkkillers and heart medications are not immune to coffee’s influence either. Caffeine can speed up the absorption of over-the-counter painkillers, increasing the risk of side effects like stomach irritation or bleeding. For those taking blood pressure or arrhythmia medications, coffee’s ability to temporarily raise blood pressure and heart rate may counteract the intended effects of the drugs.

To stay safe, Kamdar advises taking levothyroxine or bisphosphonates on an empty stomach with water, and waiting 30-60 minutes before consuming coffee or food. For those on antidepressants, antipsychotics, or heart medications, it’s crucial to discuss your caffeine habits with your doctor. Reducing intake or opting for a decaffeinated option may be necessary if you experience side effects like restlessness, insomnia, or heart palpitations.

Ultimately, while coffee may be a beloved part of many people’s daily routines, it’s important to be mindful of how it can interact with certain medications. A quick chat with your pharmacist or doctor can help you enjoy your brew with peace of mind and avoid potential complications.

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Michael Okonkwo is an experienced Middle East correspondent who has reported from across the region for 14 years, covering conflicts, peace processes, and political upheavals. Born in Lagos and educated at Columbia Journalism School, he has reported from Syria, Iraq, Egypt, and the Gulf states. His work has earned multiple foreign correspondent awards.
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